Pancreatic cancer is a malignant tumor with one of the worst prognoses among solid tumors. In Poland, it accounts for 2.2% of the total incidence of malignant neoplasms. This tumor is characterized by an aggressive course, high invasiveness, rapid progression and resistance to treatment. Despite the ongoing search for new and more effective therapies, the results of treatment of this cancer are unsatisfactory. For most patients, due to the advanced stage of cancer, palliative chemotherapy remains the only method of treatment. Therefore, under the supervision of Dr. Małgorzata Lasota, students will analyze the interactions between tyrosine kinase inhibitors and selected nanoparticles, along with an in vitro assessment of their effects on both normal and cancerous human pancreatic cells. By using such innovative compounds, it will be possible not only to target drug delivery to cells, reduce or eliminate toxicity, but also to improve the drug release kinetics. The project will be carried out in the Laboratory of Cellular Engineering and Isotope Diagnostics at the Department of Physiology, Jagiellonian University Medical College.

https://cm-uj.krakow.pl/indexn.php/collegium/aktualnosc/3356